File:Muscle protein synthesis signaling cascades.jpg
From Wikimedia Commons, the free media repository
Jump to navigation
Jump to search
Muscle_protein_synthesis_signaling_cascades.jpg (619 × 347 pixels, file size: 75 KB, MIME type: image/jpeg)
File information
Structured data
Captions
Summary
[edit]DescriptionMuscle protein synthesis signaling cascades.jpg |
English: Diagram of the molecular signaling cascades that are involved in myofibrillar muscle protein synthesis and mitochondrial biogenesis in response to physical exercise and specific amino acids or their derivatives (primarily leucine and beta-hydroxy beta-methylbutyrate).
Abbreviations and schematic representations: ■PLD: phospholipase D■PA: phosphatidic acid ■mTOR: mechanistic target of rapamycin ■AMP: adenosine monophosphate ■ATP: adenosine triphosphate ■AMPK: AMP-activated protein kinase ■PGC‐1α: peroxisome proliferator-activated receptor gamma coactivator-1α ■4EBP1: eukaryotic translation initiation factor 4E-binding protein 1 ■S6K1: p70S6 kinase ■eIF4E: eukaryotic translation initiation factor 4E ■RPS6: ribosomal protein S6 ■eEF2: eukaryotic elongation factor 2 ■RE: resistance exercise; EE: endurance exercise ■Myo: myofibrillar; Mito: mitochondrial ■AA: amino acids ■↑ represents activation ■Τ represents inhibition |
Date | |
Source | (January 2016). "Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise". Acta Physiol (Oxf) 216 (1): 15–41. DOI:10.1111/apha.12532. PMID 26010896. PMC: 4843955. Figure 1 |
Author | Brook MS, Wilkinson DJ, Phillips BE, Perez-Schindler J, Philp A, Smith K, Atherton PJ |
This chemistry image could be re-created using vector graphics as an SVG file. This has several advantages; see Commons:Media for cleanup for more information. If an SVG form of this image is available, please upload it and afterwards replace this template with
{{vector version available|new image name}} .
It is recommended to name the SVG file “Muscle protein synthesis signaling cascades.svg”—then the template Vector version available (or Vva) does not need the new image name parameter. |
This chemistry image was uploaded in the JPEG format even though it consists of non-photographic data. This information could be stored more efficiently or accurately in the PNG or SVG format. If possible, please upload a PNG or SVG version of this image without compression artifacts, derived from a non-JPEG source (or with existing artifacts removed). After doing so, please tag the JPEG version with {{Superseded|NewImage.ext}} and remove this tag. This tag should not be applied to photographs or scans. If this image is a diagram or other image suitable for vectorisation, please tag this image with {{Convert to SVG}} instead of {{BadJPEG}}. If not suitable for vectorisation, use {{Convert to PNG}}. For more information, see {{BadJPEG}}. |
Licensing
[edit]This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 06:11, 3 September 2016 | 619 × 347 (75 KB) | Seppi333 (talk | contribs) | change AA to "AA or HMB" | |
02:47, 2 September 2016 | 619 × 347 (75 KB) | Seppi333 (talk | contribs) | Reverted to version as of 02:21, 22 July 2016 (UTC) | ||
12:30, 1 September 2016 | 619 × 347 (75 KB) | Seppi333 (talk | contribs) | changed amino acids to "Leucine or HMB" | ||
02:21, 22 July 2016 | 619 × 347 (75 KB) | Seppi333 (talk | contribs) | Fixed an error in the original diagram. The "AMP:ATP" text should have had an up-arrow next to it since a high AMP:ATP ratio activates AMPK. | ||
21:34, 23 May 2016 | 619 × 347 (64 KB) | Seppi333 (talk | contribs) | User created page with UploadWizard |
You cannot overwrite this file.
File usage on Commons
The following 2 pages use this file:
File usage on other wikis
The following other wikis use this file:
- Usage on bn.wikipedia.org
- Usage on bs.wikipedia.org
- Usage on en.wikipedia.org
- Usage on fa.wikipedia.org
- Usage on ko.wikipedia.org
- Usage on pt.wikipedia.org
- Usage on th.wikipedia.org
- Usage on zh.wikipedia.org
Metadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Orientation | Normal |
---|